Adjunct Professor
Professional engagements
Professor (2019-2023)
School of Biological Sciences
RKM Vivekananda Educational and Research Institute
Belur, West Bengal
Chief Scientist (upto March 2018)
Infectious Diseases and Immunology Division
CSIR-Indian Institute of Chemical Biology
Kolkata
Professor and Coordinator (upto March 2018)
Academy of Scientific and Innovative Research
CSIR
Education
Ph.D, CSIR-Indian Institute of Chemical Biology, Kolkata, India
M.Sc. in Biochemistry, University of Calcutta, India
B.Sc. with Chemistry (Hons), Presidency College, Calcutta, India
Awards/Honours
Fellow, National Academy of Science, India
Fellow, WB Academy of Science and Technology
National Young Woman Bioscientist Award, Department of Biotechnology
Member, Guha Research Conference
Raman Research Fellowship, CSIR
DBT Overseas Associateship
CSIR Young Scientist Award
Associate, Indian Academy of Sciences
Guha Memorial Prize, Calcutta University
Areas of research interest
- Infectious Diseases: Vibrio cholerae, Helicobacter pylori
- Genetic regulation of bacterial pathogenesis
- Microbiome: Role in health and disease
Selected Publications
Infiltration to infection: Key virulence players of Helicobacter pylori pathogenicity 2024 Bhattacharjee A, O.S. Sahoo, A Sarkar, S Bhattacharya, R Chowdhury, O Mukherjee
Infection (in press)
Chakraborty P, Chowdhury R, Bhakta A, Mukhopahyay P, Ghosh S.2021 Microbiology of periodontal disease in adolescents with Type 1 diabetes Diabetes & Metabolic Syndrome: Clinical Research & Reviews 15 : 102333
Jain S, Chowdhury R, Datta M, Chowdhury G, Mukhopadhyay AK. 2019 Characterization of the clonal profile of methicillin resistant Staphylococcus aureus isolated from patients with early post-operative orthopedic implant based infections. Ann Clin Microbiol Antimicrob. doi: 10.1186/s12941-019-0307-z.
Sengupta C, Mukherjee O, Chowdhury R. 2016 Adherence to intestinal cells promotes biofilm formation in Vibrio cholerae
J Infect Dis. 214:1571-1578
Bhattacharya S, Mukherjee O, Mukhopadhyay AK, Pal AK, Dhar KK and Chowdhury R. 2016 A conserved Helicobacter pylori gene, HP0102, is induced upon contact with gastric
cells and has multiple roles in pathogenicity
J Infect Dis. 214:196-204
Sengupta C, Ekka M, Arora S, Dhaware PD, Chowdhury R*, Raychaudhuri S* 2016
Cross feeding of glucose metabolism byproducts of Escherichia coli human gut isolates and probiotic strains affect survival of Vibrio cholerae
Gut Pathog. doi: 10.1186/s13099-016-0153-x.
Baidya AK, Bhattacharya S, Chowdhury R. 2014 Role of the flagellar hook length control protein FliK and sigma-28 in cagA expression in gastric cell adhered Helicobacter pylori.
J. Infect Dis (IF 6.34)
Sengupta C, Ray S, Chowdhury R. 2014. Fine tuning of virulence regulatory pathways in enteric bacteria in response to varying bile and oxygen concentrations in the gastrointestinal tract.
Gut Pathog. 6:38. doi: 10.1186/s13099-014-0038-9. (Invited review)
Sinha S, Giri AK, Chowdhury R, Ray K. 2014 Mitochondrial genome variations among arsenic exposed individuals and potential correlation with apoptotic parameters.
Environ Mol Mutagen. 55:70-76
Raghwan, Chowdhury R. 2014 Host cell contact induces Fur-dependent expression of virulence factors CagA and VacA in Helicobacter pylori.
Helicobacter. 19:17-25. Selected as ‘Faculty of 1000 Prime’
Chatterjee E, Chowdhury R. 2013 Reduced virulence of the Vibrio cholerae fadD mutant is due to induction of the extracytoplasmic stress response
Infect Immun. 81:3935-41
Dey AK, Bhagat A, Chowdhury R. 2013 Host cell contact induces expression of virulence factors and VieA, a cyclic di-GMP phosphodiesterase, in Vibrio cholerae.
J Bacteriol. 195: 2004-10.
Pradhan S, Mallick SK, Chowdhury R. 2013 Vibrio cholerae classical biotype is converted to the viable non-culturable state when cultured with the El Tor biotype.
PLoS One. 8:e53504.
Chakraborti S, Bhattacharya S, Chowdhury R, Chakrabarti P. 2013 The molecular basis of inactivation of metronidazole-resistant Helicobacter pylori using polyethyleneimine functionalized zinc oxide nanoparticles.
PLoS One. 8:e70776
Ghosh A, Choudhury A, Das A, Chatterjee NS, Das T, Chowdhury R, Panda K, Banerjee R, and Chatterjee I.B. 2012. Cigarette smoke induces p-benzoquinone-albumin adduct in blood serum: Implications on structure and ligand binding properties.
Toxicology 292:78-89
Ray S, Chatterjee E, Chatterjee A, Paul K, and R. Chowdhury. 2011 A fadD mutant of Vibrio cholerae is impaired in the production of virulence factors and membrane localization of the virulence regulatory protein TcpP.
Infect Immun. 79:258-66.
Pradhan S, Baidya AK, Ghosh A, Paul K and R. Chowdhury. 2010 The El Tor biotype of Vibrio cholerae exhibits a growth advantage in the stationary phase in mixed cultures with the classical biotype.
J Bacteriol. 192 :955-63.
Chatterjee A and R. Chowdhury 2008 Bile and unsaturated fatty acids inhibit the binding of cholera toxin and Escherichia coli heat labile enterotoxin to GM1 receptor. Antimicrob. Agents Chemother 52: 220-224
Chatterjee A., P.K. Dutta and R. Chowdhury. 2007. Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae
Infect. Immun. 75: 1946-1953
Ghosh, A., K. Paul and R. Chowdhury 2006 Role of H-NS in colonization, motility and bile dependent repression of virulence gene expression in Vibrio cholerae.
Infect. Immun. 74: 3060-3064
Banerjee S., and R. Chowdhury. 2006 An orphan DNA (cytosine-5-)-methyltransferase n Vibrio cholerae.
Microbiology 152: 1055-1062
Chatterjee, A., S. Chaudhuri, G. Saha, S. Gupta, and R. Chowdhury. 2004 Effect of bile on the cell surface permeability barrier and efflux system of Vibrio cholerae.
J. Bacteriol. 188: 6809-6814
Paul, K., A. Ghosh, N. Sengupta and R. Chowdhury. 2004 Competitive growth advantage of non-toxigenic mutants in the stationary phase in archival cultures of pathogenic Vibrio cholerae strains.
Infect. Immun. 72: 5478-5482
Krishnan, H. H., A. Ghosh, K. Paul and R. Chowdhury. 2004. Effect of anaerobiosis on expression of virulence factors in Vibrio cholerae.
Infect. Immun. 72: 3961-3967
Sengupta N., K. Paul and R. Chowdhury. 2003 The global regulator ArcA modulates expression of virulence factors in Vibrio cholerae.
Infect. Immun. 71: 5583-5589
Mohanakumar K. P., B. Thomas, S. Sharma, D. Muralikrishnan, R. Chowdhury
and C. C. Chiueh. 2002. Nitric Oxide: An antioxidant and neuroprotector.
Ann. N. Y. Acad. Sci. 962: 389-401
Chakrabarti S., N. Sengupta and R. Chowdhury. 1999. Role of DnaK in in vitro and in vivo expression of virulence factors of Vibrio cholerae.
Infect. Immun. 67 : 1025 – 1033.
Gupta S. and R. Chowdhury. 1997 Bile affects production of virulence factors and motility of Vibrio cholerae.
Infect. Immun. 65 : 1131 – 1134.
Sahu G.K., R. Chowdhury and J. Das. 1997. The rpoH gene encoding sigma 32 homolog of Vibrio cholerae.
Gene 189 : 203 – 207
Sahu G.K., R. Chowdhury and J. Das. 1994. Heat shock proteins and heat shock protein antigens of V. cholerae. Infect. Immun. 62 : 5624 -5631.
Biswas S.K., R. Chowdhry and J. Das. 1992. A 14 kilodalton inner membrane protein of V. cholerae biotype El Tor confers resistance to Group IV infection to classical Vibrios.
J. Bacteriol. 174: 6221-6229.
Chowdhury R., S.K Biswas. and J. Das. 1989. Abortive replication of choleraphage f 149 in the biotype El Tor of Vibrio cholerae.
J. Virol. 63 : 392-397
Chowdhury R., A., Sengupta P.Ray and J. Das. 1987. Replication and packaging of
choleraphage f 149 DNA
J. Virol. 61 : 3999-4006
Chowdhury R. and J. Das. 1986. Infection by choleraphage f 138 : Bacteriophage DNA and replicative intermediates.J. Virol. 57 : 960-967
